t-Butyl p-methylbenzoate
t-Butyl p-methylbenzoate is a specialty chemical compound widely used in pharmaceutical intermediates, fragrance formulations, and organic synthesis. This high-purity ester derivative offers excellent stability and solubility characteristics, making it a preferred choice for industrial applications.
Product Specifications
- Chemical Name: t-Butyl p-methylbenzoate
- CAS Number: 71368-80-4
- Molecular Formula: C12H16O2
- Molecular Weight: 192.25 g/mol
- Appearance: Colorless to pale yellow liquid
- Purity: ≥98% (GC)
- Density: 0.98-1.02 g/cm³ at 20°C
- Boiling Point: 245-248°C
- Flash Point: >110°C
- Solubility: Soluble in organic solvents; insoluble in water
| Property | Value |
|---|---|
| Refractive Index | 1.492-1.496 (20°C) |
| Vapor Pressure | 0.01 mmHg at 20°C |
| Storage Temperature | 2-8°C |
| Shelf Life | 24 months when properly stored |
Key Applications
- Pharmaceutical intermediates synthesis
- Fragrance and flavor formulations
- UV stabilizer production
- Polymer modification agent
- Organic synthesis building block
Handling & Safety
- Use personal protective equipment (gloves, goggles)
- Avoid contact with skin and eyes
- Store in tightly closed containers in cool, dry place
- Keep away from heat sources and open flame
t-Butyl p-methylbenzoate FAQ
What are the main industrial uses of t-Butyl p-methylbenzoate?
t-Butyl p-methylbenzoate serves primarily as a versatile intermediate in pharmaceutical synthesis, particularly in the production of active pharmaceutical ingredients (APIs). It's also valued in fragrance industry for its ester characteristics, and as a building block in specialty chemical manufacturing. The compound's stability makes it suitable for polymer applications where it acts as plasticizer or modifier.
How should t-Butyl p-methylbenzoate be properly stored?
For optimal shelf life, t-Butyl p-methylbenzoate should be stored in amber glass or high-density polyethylene containers under inert atmosphere (nitrogen preferred). Maintain storage temperatures between 2-8°C in a dry environment away from direct sunlight. The container should be tightly sealed to prevent moisture absorption and oxidation. Under these conditions, the product remains stable for at least 24 months.
What safety precautions are necessary when handling t-Butyl p-methylbenzoate?
While t-Butyl p-methylbenzoate isn't classified as highly hazardous, standard chemical handling precautions apply. Use chemical-resistant gloves (nitrile recommended) and safety goggles in case of splashes. Work in well-ventilated areas or use fume hoods when handling larger quantities. Though it has relatively high flash point, keep away from ignition sources. In case of skin contact, wash immediately with soap and water; for eye contact, flush with water for at least 15 minutes and seek medical attention.
Packaging Options
| Package Size | Material | Quantity per Pallet |
|---|---|---|
| 100g | Glass bottle | 120 units |
| 500g | Glass bottle | 48 units |
| 1kg | HDPE container | 25 units |
| 5kg | HDPE drum | 4 units |
| 25kg | Steel drum | 1 unit |
Technical Notes
t-Butyl p-methylbenzoate demonstrates excellent chemical stability under normal conditions. However, it may undergo hydrolysis under strongly acidic or basic conditions at elevated temperatures. The compound is compatible with most organic solvents including alcohols, ethers, and chlorinated hydrocarbons. For analytical purposes, GC-MS is the recommended characterization method with typical retention time of 7.8 minutes using DB-5 column (30m x 0.25mm, 0.25μm film thickness).