m-Trifluoromethylphenol
m-Trifluoromethylphenol: High-Purity Chemical Compound for Industrial Applications
m-Trifluoromethylphenol (CAS 98-17-9) is a versatile fluorinated aromatic compound widely used in pharmaceutical intermediates, agrochemical synthesis, and specialty chemical manufacturing. This organic compound features a phenol group with a meta-positioned trifluoromethyl substituent, imparting unique chemical properties that make it valuable across multiple industries.
Key Product Specifications
- Chemical Name: 3-(Trifluoromethyl)phenol
- Molecular Formula: C7H5F3O
- Molecular Weight: 162.11 g/mol
- Appearance: Colorless to pale yellow liquid
- Purity: ≥98% (GC analysis)
- Boiling Point: 178-180°C
- Melting Point: 30-32°C
- Density: 1.326 g/cm³ at 25°C
- Refractive Index: n20/D 1.460
- Flash Point: 76°C
| Parameter | Specification | Test Method |
|---|---|---|
| Assay (GC) | ≥98% | ASTM E260 |
| Water Content | ≤0.5% | Karl Fischer |
| Residue on Ignition | ≤0.1% | USP 281 |
| Heavy Metals (as Pb) | ≤10 ppm | ICP-OES |
| Chloride Content | ≤50 ppm | Ion Chromatography |
Applications of m-Trifluoromethylphenol
m-Trifluoromethylphenol serves as a key building block in various chemical syntheses:
- Pharmaceutical intermediates for drug development
- Agrochemical formulations (pesticides/herbicides)
- Liquid crystal materials
- Polymer modifiers
- Electronic chemicals
Storage and Handling
Store m-Trifluoromethylphenol in a cool, dry place away from direct sunlight and oxidizing agents. Keep containers tightly closed in a well-ventilated area. Recommended storage temperature: 2-8°C. Shelf life: 24 months when properly stored.
Packaging Options
- 100g glass bottle
- 500g amber glass bottle
- 1kg polyethylene container
- 5kg stainless steel drum
- 25kg HDPE drum
Safety Information
m-Trifluoromethylphenol may cause skin and eye irritation. Use appropriate personal protective equipment including gloves, goggles, and lab coat. In case of contact, rinse immediately with plenty of water. Refer to the Safety Data Sheet (SDS) for complete handling instructions.
FAQ About m-Trifluoromethylphenol
Q: What is the shelf life of m-Trifluoromethylphenol?
A: When stored properly in sealed containers at recommended temperatures (2-8°C), m-Trifluoromethylphenol maintains its quality for up to 24 months. Always check for color changes or precipitation before use in sensitive applications.
Q: Can m-Trifluoromethylphenol be used in pharmaceutical synthesis?
A: Yes, m-Trifluoromethylphenol is commonly used as a pharmaceutical intermediate, particularly in the synthesis of active pharmaceutical ingredients (APIs). It meets typical purity requirements for pharmaceutical applications (≥98%) and can be further purified if needed.
Q: What analytical methods are suitable for testing m-Trifluoromethylphenol purity?
A: Gas chromatography (GC) with flame ionization detection is the standard method for purity analysis. Additional characterization can be performed using HPLC, NMR (1H and 19F), and mass spectrometry. For trace impurities, GC-MS provides excellent sensitivity.
Regulatory Status
m-Trifluoromethylphenol is not currently listed on any major chemical inventories' restricted substance lists. However, users should verify regulatory status for their specific application and region. The compound is classified as hazardous according to OSHA Hazard Communication Standard (29 CFR 1910.1200).
Customization Services
We offer custom synthesis services for m-Trifluoromethylphenol derivatives and related compounds. Our R&D team can develop specialty grades with enhanced purity or modified physical properties to meet specific application requirements.
Quality Assurance
Every batch of m-Trifluoromethylphenol undergoes rigorous quality control testing including:
- Identity confirmation (FTIR, NMR)
- Purity analysis (GC, HPLC)
- Physical property verification
- Microbial testing (for pharmaceutical grades)
- Stability testing
Additional FAQ About m-Trifluoromethylphenol
Q: What solvents are compatible with m-Trifluoromethylphenol?
A: m-Trifluoromethylphenol shows good solubility in common organic solvents including methanol, ethanol, acetone, ethyl acetate, dichloromethane, and toluene. It has limited solubility in water (approximately 1.2 g/L at 20°C).
Q: How should m-Trifluoromethylphenol be disposed of properly?
A: Dispose of m-Trifluoromethylphenol according to local, state, and federal regulations. Small quantities can be neutralized with base and washed down with excess water if permitted. For larger quantities, consult licensed waste disposal services.
Q: What safety precautions are needed when handling m-Trifluoromethylphenol?
A: Always work in a fume hood with proper ventilation. Use chemical-resistant gloves (nitrile or neoprene), safety goggles, and protective clothing. Avoid inhalation and skin contact. Have emergency eyewash and shower available in the work area.
Shipping Information
m-Trifluoromethylphenol is classified as a hazardous material for transportation. We ship globally via approved carriers with all required documentation. Smaller quantities can be sent via express courier services, while bulk quantities require specialized chemical transport.
For technical inquiries about m-Trifluoromethylphenol, including custom formulations, purity requirements, or large volume orders, please contact our technical sales team for expert consultation and support.